Activation of casp6 was upstream of casp3 7 activation and its inhibition was sufficient to prevent cell death in our system. Caspase 9 belongs to a family of caspases cysteine aspartic proteases involved in apoptosis and cytokine. Caspase 9 homologs have been identified in all mammals for which they are known to exist such as mus musculus and pan troglodytes.
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